Crossword Clue:

ETERNALISE to make eternal

AnswerCrossword Clue
DAMNConsign to eternal misery
ROMAEternal City, to Italians
DAMNSSends to eternal punishment
DAMNDoom to eternal punishment
ROMAThe Eternal City, to natives
EOSGoddess who gained immortality for her lover but forgot to ask for eternal youth (whoops!)