Crossword Clue:

the central subject of a work of art

AnswerCrossword Clue
IMACSThey're "as much a work of art" as "state of the art"
MCESCHERSubject of an art museum in The Hague
THEKISS1889 work of art deemed unsuitable for general display at the 1893 Chicago World's Fair
MERRYPRANKSTERSSubject of the 1968 work