| Answer | Crossword Clue |
|---|---|
| OPIATE | It's a downer |
| QUAALUDE | It's a downer |
| OPIATE | It's a real downer |
| MOPE | Be a downer |
| SOT | Quite a downer? |
| RAINER | A shower-downer. |
| MOPE | Be a Debbie Downer |
| NOFUN | Like a Debbie Downer |
| downers | DOWNER, a depressant drug |
| OPIATE | Drug that's a downer |
| SOT | One who is quite a downer? |
| downers | a weak, sick, or crippled animal in shipment that is down and cannot get up often used attributively a downer cow |
