Answer: LOCO

AnswerCrossword Clue
LOCOCrazy, in Cozumel
LOCOScrewy
LOCODaffy
LOCONuts or crackers?
LOCOCrackers
LOCOOff one's rocker, and a hint to what the four longest puzzle answers have in common
LOCONot right in the head
LOCOOut of one's gourd
LOCOPrefix with weed or motion
LOCOBats or bonkers
LOCOOff your rocker
LOCONuts
LOCOCrazy
LOCOIn ... parentis (acting as mom or pop)
LOCOBananas, nuts, or crackers
LOCOCrazy in la cabeza
LOCOCuckoo, in CancĂșn
LOCOWacky
LOCOCrazy, in CancĂșn
LOCOCuckoo
locoin the register as written used as a direction in music
LOCOBananas
LOCOInsane
LOCOWeed or motive starter
LOCOPlumb crazy
LOCOTouched
LOCOOff one's trolley
LOCOCrazy, in Texas
LOCOBats
LOCOBonkers
LOCOCrackers or nuts
LOCOIn .. parentis
LOCOHaywire
LOCOIn ... parentis
LOCOBerserk
LOCOIn ... parentis: acting as a parent
LOCOMad
LOCOOff one's rocker
LOCOTouched in the head
LOCONot all there