Answer:

LOIS

AnswerCrossword Clue
LOISActress Nettleton
LOISPartner for Clark
LOISRole for Teri
LOISHi's helpmate, in the comics
LOISSuperman's Lane
LOISSuperman's girl
LOISHi's comics wife
LOISClark's colleague
LOISThe Daily Planet name
LOISClark's heartthrob
LOIS"Family Guy" mom
LOISLane in Metropolis
LOISClark's cohort in comics
LOISColleague of Clark
LOISSuperman-smitten Lane
LOISWorker with Jimmy and Kent
LOISSuperman's sweetie
LOISChildren's author Lowry
LOISSci-fi author ... McMaster Bujold
LOISLane in the comics
LOISLowry of children's lit
LOISClark's partner
LOISClark's love
LOISHi's comics mate
LOISDaily Planet reporter
LOISFictional reporter Lane
LOIS"Malcolm in the Middle" mom
LOISDaily Planet reporter Lane
LOISSuperman lover Lane
LOISTwo-time Newbery Medal winner Lowry
LOISAssociate of Jimmy
LOISLane of The Daily Planet
LOISNewbery Medal winner Lowry
LOISPlanet name?
LOISClark's crush
LOISOft-rescued comics heroine
LOISHi's spouse, in comics
LOISClark's coworker
LOISKisser of "super-lips"
LOISClark's wife in the comics