Answer:

LOST

Answer	Crossword Clue
LOST	Disoriented
LOST	In need of directions
LOST	Like the boys in "Peter Pan"

LOST	"... In Space"
LOST	Requiring directions
LOST	In need of a map
LOST	In the middle of nowhere
LOST	Gone astray
LOST	TV show that even its writers now admit was generally directionless
LOST	Down the drain
LOST	Bewildered

LOST	Story of Oceanic Flight 815
LOST	2005 Emmy winner for Outstanding Drama Series
LOST	Got beaten
LOST	Misplaced
LOST	Unable to find one's way
LOST	Missing
LOST	Totally confused
LOST	Hit ABC drama about plane crash survivors

LOST	Needing a map
LOST	ABC drama filmed mostly in Hawaii
LOST	ABC drama set on a remote island
LOST	Going around in circles
LOST	Absorbed
LOST	Complex ABC drama
LOST	In unfamiliar territory, maybe
LOST	TV series filmed on Oahu

LOST	Wasted, as a chance
LOST	At sea
LOST	Completely flummoxed
LOST	Drama that began with a plane crash
LOST	Going around in circles, maybe
LOST	More than just hard to find
LOST	Quite befuddled
LOST	Without hope

LOST	2000s TV drama that ended in a church
LOST	Confused
LOST	Late for a party, maybe
LOST	Off-track
LOST	Like some causes