Answer:

MADMAGAZINE

AnswerCrossword Clue
MADMAGAZINE"Spy vs. Spy" home
MADMAGAZINESatirical periodical since 1952
MADMAGAZINEVenerable satire publication
MADMAGAZINEAlfred E. Neuman's publication: 2 wds.
MADMAGAZINEPublication since 1952
MADMAGAZINEHumor publication since 1952
MADMAGAZINEWacky publication?
MADMAGAZINEAlfred is its cover boy
MADMAGAZINEIt began as a comic book in 1952