Answer:

OPUS

AnswerCrossword Clue
OPUSMagnum .. (great work)
OPUSMusical number?
OPUSMusical piece
OPUSMusical work
OPUSWork by Beethoven
OPUS"Bloom County 2015" character
OPUSWork of classical music
OPUSPiece of work
OPUSMajor work
OPUSMr. Holland's masterpiece
OPUSComposition
OPUSWork
OPUSWork of a composer
OPUSNovel or symphony
OPUSArtistic work
OPUSMagnum ..
OPUSNumbered composition
OPUSBeethoven's Fifth, e.g.
OPUS"... No. 1" (Tommy Dorsey hit)
OPUSLiterary work
OPUS"Mr. Holland's ..."
OPUSMusical composition
OPUSNumbered work
OPUSWork with a number, often
OPUSCatalogued work
OPUSMagnum ..: great work
OPUSMusical work with a number
OPUS"Mr. Holland's .."
OPUSComic strip penguin
OPUSNumbered musical work
OPUS.. number
OPUSBreathed's comics penguin
OPUSMusic with a number
OPUSNumbered Beethoven work, e.g.
OPUSWork with notes
OPUSNumbered piece
OPUSNumbered musical piece
OPUSMusical number
OPUSSonata, e.g.
OPUSComic-strip penguin