Answer:

UNLOOSEN

AnswerCrossword Clue
UNLOOSENPrepare for takeoff?
UNLOOSENSet free
UNLOOSENOpen
UNLOOSENRelease, redundantly
UNLOOSENFree from restraint
UNLOOSENPrepare to take off, perhaps
UNLOOSENLet free
UNLOOSENUntie, as a restraint
UNLOOSENFree from binding