Crossword Clue:

to cause to become an orphan

Answer	Crossword Clue
ENURE	Cause to become hardened to
INURE	Cause to become used to.
ENURE	Cause to become hardened to (var.)

ANNIEGETYOURGNU	Caution to an orphan girl not to leave her wildebeest behind?
RENDER	Cause to become
ENDEAR	Cause to become admired
ENDEAR	Cause to become beloved
REFLOAT	Cause to become buoyant again
DISPERSE	Cause to become separated in flight.