Whats Up Doc? is one
Crossword Clue

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AnswerCrossword Clue
FARCE

"What's Up, Doc?" is one

BLANC

''What's up Doc?" is his line

DONE

Get Up Kids "What's said is ... and plain to see"

LINE
"What's your sign?" is one
LINE
"So, what's your sign?" is one
ASTRONOMEROne who knows what's up?
AGNOSTICOne who's not sure what's up?
IDIOM"Up the creek," is one
MAIDOne whose business is picking up
NEATFREAKOne whose business is picking up?
ROLEMODELOne who is looked up to
ITSATIEComment when no one is up
NEATNIKOne whose work is picking up?
ATBOTTOMWhere one is always looking up?
MAIDOne whose business is picking up?
ASSTOne whose job is backing up: Abbr.
SLOBOne whose work is not picking up?
FARMEROne whose work is always cropping up?
PILOTOne whose work is up in the air?
OFFSTimes when one is not up to par.
KAYAKEROne who is up the creek with a paddle
HOOTOWLOne might wake you up if your window is open
SIXWhen one hand is up and the other is down
AMPOne could go up to 11 in "This Is Spinal Tap"
EDWARDLEARThere once was an author from Britain - Who laughed at the poems he'd written - "Five lines to a verse - Is so very terse - I can finish 'em up in one sittin'."