| Answer | Crossword Clue |
|---|---|
| POSTRENAISSANCE | After the 16th century in Europe. |
| RENAISSANCEMAIN | Water pipe in 16th-century Europe? |
| PALATINO | Typeface family named after a 16th century Italian calligrapher |
| MDII | Early in the 16th century. |
| MLII | Date in the 16th century |
| INCAS | Pizzaro's victims in the 16th century. |
| INCA | Peruvian conquered in the 16th century |
| SEAPOWERS | Spain and England in the 16th century |
| INCA | Member of an empire that ended in the 16th century |
