| Answer | Crossword Clue |
|---|---|
| MORIARTY | Archenemy of Holmes |
| NATASHA | Archenemy of "Moose and Squirrel" |
| SKELETOR | Archenemy of Mattel's He-Man |
| DRDOOM | Archenemy of the Fantastic Four |
| EGGMAN | Rotund archenemy of Sonic the Hedgehog |
| DOOM | Dr. ... (archenemy of the Fantastic Four) |
| ARES | Archenemy in the video game "God of War" |
