| Answer | Crossword Clue |
|---|---|
| THESANTAFETRAIL | Frontier way to the Southwest |
| THEOREGONTRAIL | Frontier way to the Northwest |
| CUMBERLANDROAD | Frontier way to the Midwest, with "The" |
| TED | Low-cost competitor of Frontier and Southwest |
| SPACE | "The final frontier," to Captain Kirk |
| CACTI | They connect to points in the Southwest |
