| Answer | Crossword Clue |
|---|---|
| IRENE | Holmes adversary Adler |
| IRENE | Sherlock's adversary Adler |
| IRENE | Holmes friend Adler |
| IRENE | Sherlock Holmes' Ms. Adler |
| IRENE | Sherlock Holmes' friend Adler |
| IRENE | Adler who outwitted Sherlock Holmes |
| IRENE | Adler admired by Sherlock Holmes |
| IRENE | Adler in Sherlock Holmes stories |
| IRENE | Adler of Sherlock Holmes stories |
| IRENE | Adler of Sherlock Holmes lore |
| IRENE | Adler in a Sherlock Holmes tale |
