| Answer | Crossword Clue |
|---|---|
| AGONY | It's a major pain |
| ACHE | It's a pain |
| AGONY | It's a big pain |
| OTITIS | It's a pain in the ear |
| SAGA | It's a major account |
| SAGA | It's a major report |
| COAL | Its burning is a major source of Beijing smog |
| PADRES | Only major league team without a no-hitter to its credit |
| IRS | Longtime record label that shares its inits. with a major government agcy. |
