| Answer | Crossword Clue |
|---|---|
| CSI | Procedural that aired its 250th episode in 2011 |
| SIMPSONS | "The ..," sitcom that recently aired its 250th episode |
| LOST | Series that aired its final episode in May 2010 |
| WHO | The .. (rock band that lent its voices to 15-Across's 250th episode) |
