| Answer | Crossword Clue |
|---|---|
| upriver | Toward or situated at a point nearer the source of a river |
| downriver | Toward or situated at a point nearer the mouth of a river |
| upstream | Moving or situated in the opposite direction from that in which a stream or river flows; nearer to the source |
| upstream | Situated in or toward the part of a sequence of genetic material where transcription takes place earlier than at a given point |
| downstream | Situated in or toward the part of a sequence of genetic material where transcription takes place later than at a given point |
