Answer:

IRK

Answer	Crossword Clue
IRK	Bother
IRK	Peeve
IRK	Tick off

IRK	Tee off
IRK	Bug
IRK	Vex
IRK	Try
IRK	Get under one's skin
IRK	Run afoul of
IRK	Perturb
IRK	Rub the wrong way

IRK	Irritate
IRK	Annoy
IRK	Exasperate
IRK	Nettle
IRK	Get to
IRK	Do some button-pushing, so to speak
IRK	Rile up
IRK	Drive up the wall

IRK	Aggravate
IRK	Drive up the wall, so to speak
IRK	Miff
IRK	Get on one's nerves
IRK	Rankle
IRK	Get one's goat
IRK	Put in a pet
IRK	Ruffle

IRK	Stick in one's craw
IRK	Get on the nerves of
IRK	Get under the skin of
IRK	Bug a bit
IRK	Drive to distraction
IRK	Grate on
IRK	Really get to
IRK	Provoke

IRK	Really bug
IRK	Bother a lot
IRK	Really annoy
IRK	Needle
IRK	Rile