Answer: irk

AnswerCrossword Clue
IRKGo against one's grain
IRKBe a pain
IRKSet off
IRKTrouble
IRKReally pester
irkto irritate or annoy
irkto annoy or weary
IRKTry the patience of
IRKInflame
IRKBadger
IRKGravel
IRKBug or annoy
IRKRattle one's cage
IRKMake upset
IRKAnger
IRKIt may be in front of some
IRKGall
IRKPiss off
IRKBug big-time
IRKBother the heck out of
IRKTrouble.
IRKBother greatly
IRKGet disgruntled
IRKChafe
IRKBe a thorn in the side of
IRKAnnoy.
IRKBore.
IRKMake uneasy.
IRKBother.
IRKAnnoy persistently.
IRKPut out
IRKWeary.
IRKMake tired.
IRKNettle.
IRKProvoke.
IRKVex.
IRKIrritate.
IRKWear on
IRKTire
IRKBore