Answer: appalachia

AnswerCrossword Clue
APPALACHIAUS coal region
APPALACHIAWhere bluegrass music is popular
APPALACHIADepressed area of U.S.
APPALACHIAPart of western Maryland
APPALACHIAHighland region of the U.S.
APPALACHIAArea of Great Society concern
APPALACHIARegion in the eastern U.S.
APPALACHIAPittsburgh is its most populous city
APPALACHIACoal-mining center