Answer: asshole

AnswerCrossword Clue
ASSHOLEWord shouted at an aggressive driver
assholea worthless person (the anus)
assholethe opening at the lower end of the alimentary canal, through which the solid refuse of digestion is excreted
assholestupid, mean, or contemptible
assholea. stupid, mean, or contemptible person b. the worst part of a place or thing