Answer:

bane

AnswerCrossword Clue
BANECurse
BANEOpposite of 5D
BANERuin
BANEDeadly poison
BANERuination
BANEThorn in one's side
BANECanker
BANECause of ruination
BANESource of ruin
BANEScourge
BANEBugaboo
BANENemesis
BANESomething terrible
BANEDownfall
BANEBatman foe
BANEBringer of ruin
BANE"I will not be afraid of death and ...": "Macbeth"
BANESpoiler
BANEPoisonous-plant suffix
BANEPlant-name ender
BANECause of ruin
BANESun, to Frosty
BANEDennis, to Mr. Wilson
BANEPlague
BANEUndoing
BANEProverbial thorn
BANEAffliction
BANEPoison
BANEGarlic, to a vampire
BANECause of harm
BANEFlea, to Fido
BANEProblem source
BANEDestruction
BANEReason for ruin
BANESource of aggravation
BANECause of misery
BANESource of irritation
BANESource of misery
BANEWoe
BANEDownfall cause