Answer: breakthrough

AnswerCrossword Clue
BREAKTHROUGHEnd of the factoid
BREAKTHROUGHSudden advance, as in science
BREAKTHROUGHMake a sudden advance
BREAKTHROUGHScientific triumph.
BREAKTHROUGHMilestone of success
BREAKTHROUGHGood for a scientist, bad for a roofer
breakthroughA sudden, dramatic, and important discovery or development, esp. in science
breakthroughA significant and dramatic overcoming of a perceived obstacle, allowing the completion of a process
breakthroughan offensive thrust that penetrates and carries beyond a defensive line in warfare