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Answer:

despair

Answer	Crossword Clue
DESPAIR	Feeling of hopelessness
DESPAIR	Low state
DESPAIR	Lose hope

DESPAIR	Lose heart
DESPAIR	Hopelessness
DESPAIR	Bad thing to sink into
DESPAIR	Film noir feature
DESPAIR	Give up

Crossword

a puzzle consisting of a grid of squares and blanks into which words crossing vertically and horizontally are written according to clues.