Answer:

despairs

Answer	Crossword Clue
DESPAIRS	Loses hope
DESPAIRS	Abandons hope
DESPAIRS	Has the blues

DESPAIRS	Has a heavy heart
DESPAIRS	Gives up
DESPAIRS	Gives up hope.
DESPAIRS	Loses hope.
DESPAIRS	Is ready to give up the ship
DESPAIRS	Loses heart

Crossword

a puzzle consisting of a grid of squares and blanks into which words crossing vertically and horizontally are written according to clues.