Answer: disaster

AnswerCrossword Clue
DISASTERSandy, say
DISASTEREarthquake, e.g.
DISASTERTrain wreck, e.g.
DISASTERYou may flirt with it
DISASTERHuge flop
DISASTERWorst-case scenario
DISASTERBig snafu
DISASTERMegaflop
DISASTERGreat misfortune
DISASTERTitanic sinking, for one
DISASTERMajor flop
DISASTERTotal failure
disasterAn event or fact that has unfortunate consequences
disastera calamity (a disaster)
disasterA person, act, or thing that is a failure
disasterDenoting a genre of films that use natural or accidental catastrophe as the mainspring of plot and setting
disasterA sudden event, such as an accident or a natural catastrophe, that causes great damage or loss of life
DISASTERFlood, say
DISASTERCalamitous event.
DISASTERWhen the Red Cross goes into action.
DISASTERRuinous mischance.
DISASTERSudden misfortune.
DISASTERUnfortunate event.
DISASTERCalamity.
DISASTERCalamity
DISASTERBomb
DISASTERBig turkey
DISASTERFiasco
DISASTEREarthquake, perhaps
DISASTERCatastrophe
DISASTERIrwin Allen film plot device
DISASTERType of area or film
DISASTERUtter failure