Answer: domesticate

AnswerCrossword Clue
DOMESTICATEShakespeare's tamed shrew
DOMESTICATEMake tame
domesticateMake (someone) fond of and good at home life and the tasks that it involves
domesticateto bring into domestic use
domesticateCultivate (a plant) for food
domesticateTame (an animal) and keep it as a pet or for farm produce