Answer: enervated

AnswerCrossword Clue
ENERVATEDSapped
ENERVATEDOn the ropes
ENERVATEDReally exhausted
ENERVATEDWeakened.
enervatedENERVATE, to weaken (to make weak (lacking strength))
enervatedCause (someone) to feel drained of energy or vitality; weaken