Answer: heartache

AnswerCrossword Clue
HEARTACHEDeep sorrow
HEARTACHESorrow.
HEARTACHESadness.
HEARTACHEAnguish of a sort.
HEARTACHESubject of many a sad ballad
HEARTACHEGrief
HEARTACHEAnguish
HEARTACHELovelorn doctor's diagnosis?
HEARTACHEEmotional pain
HEARTACHEEmotional anguish
heartacheEmotional anguish or grief, typically caused by the loss or absence of someone loved
heartachesorrow, anguish