Answer: heartbreak

AnswerCrossword Clue
HEARTBREAKAnguish after a romantic split
HEARTBREAK"The ... Kid" (1972 Neil Simon comedy)
HEARTBREAK".. Hotel" (Elvis tune)
HEARTBREAKShaw "House."
HEARTBREAKSorrow
HEARTBREAKShaw's "... House"
HEARTBREAK1972 Charles Grodin film, with "The"
HEARTBREAKLover's hurt
heartbreakcrushing grief, anguish, or distress
heartbreakOverwhelming distress