Answer: heckler

AnswerCrossword Clue
HECKLERStand-up's headache
HECKLERVociferously vocal audience member
HECKLERClub comic's bane
HECKLERComic bane
HECKLERTarget of an ad-lib comeback
HECKLERPest in the audience.
HECKLERPest in the audience
HECKLERAudience troublemaker
HECKLERComedy club razzer
HECKLERComedy club annoyance
HECKLERComic's bane
hecklerone who heckles (to harass a speaker)
hecklerto harass (a speaker) with comments or questions