Answer: hub

AnswerCrossword Clue
HUBWhere planes are often changed
HUBWhere the action is
HUBCenter of operations, to an airline
HUBSpokes' center
HUBBoston, with "the"
HUBO'Hare, for one
HUBWheel's center
HUBMajor airport
HUBCore
HUBDestination for a Trivial Pursuit winner
HUBNexus
HUBUS Airways has one in Phoenix
HUBAirline locale
HUBNerve center
HUBBoston's nickname
HUBConnecting flight site
HUBWhere some routes meet
HUBAirport with many connecting flights
HUBWheel center
HUBBub or cap opener
hubthe central part of a wheel
HUBFlight-connection site
HUBFocal point
HUBBoston
HUBBoston nickname
HUBBoston sobriquet
HUBWhere radii meet
HUBCenter
HUBAxle attachment
HUBBoston moniker
HUBAirline's main airport
HUBAxle end
HUBWhere spokes meet
HUBBusy airport
HUBWheel part
HUBFocus of activity
HUBAtlanta, for Delta Airlines
HUBCenter of activity
HUBO'Hare, for United Airlines
HUBAir base?