Answer: nastiest

AnswerCrossword Clue
NASTIESTMost malicious
nastiest(of an injury, illness, or accident) Having caused harm; severe
nastiestHighly unpleasant, esp. to the senses; physically nauseating
nastiestRepugnant to the mind; morally bad
nastiest(of the weather) Unpleasantly cold or wet
nastiest(of a person or animal) Behaving in an unpleasant or spiteful way
nastiestAnnoying or unwelcome
nastiestPhysically or mentally damaging or harmful
nastiestNASTY, ill-natured
NASTIESTLeast pleasant
NASTIESTMost unpleasant
NASTIESTWorst, weather-wise
NASTIESTMost offensive
NASTIESTUnrivaled at malice
NASTIESTWorst, weatherwise
NASTIESTWorst and meanest.
NASTIESTTops in turpitude
NASTIESTTops in malice
NASTIESTMost spiteful