Answer: okeechobee

AnswerCrossword Clue
OKEECHOBEEFlorida's largest lake
OKEECHOBEELargest lake in Florida
OKEECHOBEEFourth-largest lake completely within U.S. borders
OKEECHOBEEFourth-largest lake completely within US borders
OKEECHOBEELake by the Everglades
OKEECHOBEEFlorida county or its seat
OKEECHOBEEFlorida lake.
OKEECHOBEEEverglades lake
OKEECHOBEESouthern lake whose name comes from Muskogean for "big water"
OKEECHOBEELocals call it the "Big O"
OKEECHOBEELarge Florida lake