Answer:

pest

AnswerCrossword Clue
PESTPain in the neck
PESTRoach or termite
PESTReal pain
PESTNuisance
PESTLittle noodge
PESTTermite or gnat
PESTOne getting shooed
PESTAnnoyance
PESTPain in the you-know-what
PESTObnoxious one
PESTRat or roach
PESTRaid target
PESTBother
PESTTrying type
PESTGarden interloper
PESTFly in the face of someone?
PESTNudnik
PESTOne who 26-Across
PESTUnwelcome guest
PESTIrksome type
PESTCockroach or termite
PESTExterminator's target
PESTAnnoying type
PESTOrkin victim
PESTReal pill
PESTRaid victim
PESTAnnoyer
PESTIrritant
PESTPersistent annoyer
PESTNoodge
PESTD-Con target
PESTAdamant ant?
PESTButtinsky
PESTTeaser
PESTBotherer
PESTIrk-aholic?
PESTPlague
PESTBuzzy one
PESTNudge
PESTPain of a sort