Answer: pioneered

AnswerCrossword Clue
PIONEEREDGot the ball rolling
PIONEEREDLed the way
PIONEEREDBlazed a trail
PIONEEREDTrailblazed
PIONEEREDStarted with pi + 1 before 500 (9)
PIONEEREDSpearheaded
pioneeredopen or prepare for others to follow
pioneeredto act as a pioneer pioneered in the development of airplanes
pioneeredoriginate or take part in the development of
pioneeredttle
pioneeredPIONEER, to be first in a new field of enterprise