Answer:

poison

AnswerCrossword Clue
POISONContaminate
POISONLethal stuff
POISONWarning label word
POISONWord seen on a skull and crossbones
POISONCorrupt
POISONTaint
POISONWhodunit weapon
POISONHemlock, for one
POISONSkull-and-crossbones stuff
POISONWhat Mr. Yuk labels
POISONToxicology topic
POISONSomething harmful
POISONToxic substance
POISONToxin.
POISON... hemlock.
POISONHemlock, for example.
POISONVenom.
POISONKind of pen
POISONBorgia potion
POISONAnother man's meat
POISONArsenic, e.g.
POISONPesticide
POISONArrow application
POISONExterminator's option
POISONNegative influence
POISONMurder method in Christie's "A Pocket Full of Rye"
POISONStaple of Agatha Christie mysteries
POISONCause of Romeo's death
POISONToxic stuff
POISONVenom
POISONStrychnine
POISONScull-and-crossbones stuff
POISONToxicant
POISONArsenic e.g.
POISONStrychnine e.g.
POISONFeature of many a whodunit
POISONWhodunit staple
POISONDownfall in many an Agatha Christie novel
POISONOne of the nine weapons in 2008's expanded version of Clue