Answer:

prez

AnswerCrossword Clue
PREZW., once, and O now
PREZTitle sought by Hil, Jeb, et al.
PREZChief exec
PREZBiz honcho
PREZHead honcho
PREZPolitical cartoon subject, informally
PREZCountry runner
PREZInformal title
PREZInformal leader
PREZBig boss, informally
PREZJack or Ike, once
PREZTop suit
PREZHead honcho, briefly
PREZVeep's boss
PREZDubya, Abe, or Cal
PREZBarack Obama, familiarly
PREZDubya, once
PREZBiz biggie
PREZInformal D.C. title
PREZWhite House resident, informally
PREZIke, in the '50s
PREZOval Office honcho
PREZU.S. head, casually
PREZAbe or Dick
PREZCompany VIP
PREZGeorge W. or Bill, slangily
PREZChief exec, in tabloids
PREZHead honcho, perhaps
PREZInformal DC title
PREZCompany boss, for short
PREZTop banana
PREZOne in charge, informally
PREZBig kahuna
PREZBiz bigwig
PREZBig boss
PREZBig boss, briefly
PREZBig enchilada
PREZDubya's title
PREZNickname of tenor saxophonist Lester Young
PREZOval Office figure, familiarly