Answer: profoundest

AnswerCrossword Clue
profoundest(of a subject or thought) Demanding deep study or thought
profoundest(of a disease or disability) Very severe; deep-seated
profoundestPROFOUND, intellectually deep
profoundestAt, from, or extending to a great depth; very deep
profoundest(of a person or statement) Having or showing great knowledge or insight
profoundest(of a state, quality, or emotion) Very great or intense