Answer: raspiest

AnswerCrossword Clue
RASPIESTMost rough-sounding
RASPIESTMost harsh, as a voice
RASPIESTMost in need of a lozenge
RASPIESTMost hoarse-sounding
RASPIESTMost grating
raspiestRASPY, rough (uneven (not even))
raspiesteasily annoyed; irritable
raspiestharsh; grating; rasping