Answer: smallpox

AnswerCrossword Clue
SMALLPOXIts last U.S. case was in 1949
SMALLPOXHealth scourge now deemed eradicated
SMALLPOXEradicated disease
smallpoxAn acute contagious viral disease, with fever and pustules usually leaving permanent scars. It was effectively eradicated through vaccination by 1979
smallpoxa virus disease