Answer: sourest

AnswerCrossword Clue
SOURESTMost unpleasant
sourestdisagreeable
sourestSOUR, sharp or biting to the taste
sourestspoiled
sourestacid in taste; tart
sourestto make or become sour
SOURESTMost kumquat-esque
SOURESTMost peevish
SOURESTMost fermented.
SOURESTMost ill-tempered
SOURESTMost like a lemon
SOURESTMost vinegary
SOURESTMost off-pitch
SOURESTMost tart
SOURESTMost bitter
SOURESTTart to the max
SOURESTProduces the biggest pucker