Answer: thalidomide

AnswerCrossword Clue
thalidomideA drug formerly used as a sedative, but withdrawn in the early 1960s after it was found to cause congenital malformation or absence of limbs in children whose mothers took the drug during early pregnancy
thalidomidea non-barbiturate sedative drug, withdrawn in 1961 because found to cause malformation in the fetus if taken during pregnancy