Answer: untune

AnswerCrossword Clue
UNTUNERender out of pitch
UNTUNENegatively affect the pitch of
UNTUNEDiscompose
UNTUNEPut out of condition, as a piano
UNTUNEDeliberately disharmonize
UNTUNEDisharmonize
untuneto put out of tune
untuneto render or cause to become out of tune
untuneto discompose; upset, as the mind or emotions