Answer:

worry

Answer	Crossword Clue
WORRY	Lose sleep
WORRY	It "often gives a small thing a big shadow": old proverb
WORRY	Fret

WORRY	"What, me ...?" (Mad magazine motto)
WORRY	End of Alfred E. Neuman's slogan
WORRY	Stew
WORRY	Anxiety
WORRY	Be fretful
WORRY	Gray hair dye.
WORRY	Care.
WORRY	Vexation.

WORRY	Bother.
WORRY	Fret.
WORRY	Angst.
WORRY	Fret or chafe
WORRY	Topic of quotation below
WORRY	Trouble
WORRY	Concern
WORRY	Dog or hound

WORRY	"What, me ...?"
WORRY	Cause of wrinkles
WORRY	"Interest paid on trouble before it falls due," per W. R. Inge
WORRY	Cause of fitful sleep
WORRY	Producer of wrinkles, it's said
WORRY	"What, me ...?": Alfred E. Neuman line
WORRY	Lose sleep over
WORRY	Distress

WORRY	Kind of beads
WORRY	Show concern
WORRY	Lose sleep over (with "about")
WORRY	Be in a fretful mood